For this year’s Biology Project we will be building light-responsive genetic circuits in E.coli!
Our first goal will be to implement a system to make the bacteria generate colour changes in their environment in response to light. Then we intend to move on to a genetic construct which will allow the bacterial colony to perform edge detection i.e. only to produce colour changes where the light / dark boundary falls over the colony.
Finally, we hope to be able to extend previously published work by generating a circuit enabling colonies to perform high-pass filtering, resulting in a kind of image sharpening behaviour. We expect computational modelling of the system will play a significant role in making this possible!
To dig into the finer details of the circuits we will be using, have a look at: